Search on: IFIH1 INTERFERON-INDUCED HELICASE 
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Descriptor English:   Interferon-Induced Helicase, IFIH1 
Descriptor Spanish:   Helicasa Inducida por Interferón IFIH1 
Descriptor Portuguese:   Helicase IFIH1 Induzida por Interferon 
Synonyms English:   CADM-140 Autoantigen
Helicard
IFIH1 Protein
Interferon Induced with Helicase C Domain 1
Interferon-Induced Helicase C Domain-Containing Protein 1
Melanoma Differentiation-Associated Protein 5
Autoantigen, CADM-140
CADM 140 Autoantigen
Helicase, IFIH1 Interferon-Induced
IFIH1 Interferon-Induced Helicase
Interferon Induced Helicase C Domain Containing Protein 1
Interferon Induced Helicase, IFIH1
Melanoma Differentiation Associated Protein 5  
Tree Number:   D08.811.913.696.445.735.720.249.875
Definition English:   A DEAD box RNA helicase that contains two N-terminal CASPASE ACTIVATION AND RECRUITMENT DOMAINS. It functions as a sensor of viral NUCLEIC ACIDS such as DOUBLE-STRANDED RNA and activates the INNATE IMMUNE RESPONSE by inducing the expression of INTERFERON-ALPHA and INTERFERON-BETA. It may also regulate cell growth and APOPTOSIS. 
History Note English:   2017 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   56507 
Unique Identifier:   D000072640 

Occurrence in VHL:
 

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